AttheUniversityofBerninSwitzerland,researchershavedevelopedthePanoramicOpto-ElectricalMeasurementandStimulation(POEMS)system,whichallowsthemtoconductadvancedoptogeneticexperimentswithmousehearts.Thedevice,whichcontainsavolumeintowhichamouseheartcanbeplaced,letstheSwissteamstimulatevariouscelltypesusinglight,andthenmeasuretheresultingelectricalresponse.Previously,scientistshadnowaytotrackelectricalactivityandprovideaccurateopticalstimulationatthesametime.Thenewtechnologymayhelptodeterminethecontributionofvariouscelltypestocardiacfunctionanddisease.
Theelectricalimpulsesthattriggertheheartbeatareafundamentalpartofcardiacfunction,andwhentheygoawry,arrhythmiascanresult.Oncethoughttheexclusiveresponsibilityofcardiacmusclecells,thereisevidencethatothercelltypes,suchascardiacfibroblasts,mayplayaroleinthisprocess.Someofthisevidencehasbeenobtainedusingoptogenetics,atechnologyinwhichcellsaregeneticallymodifiedtobe
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